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phosphatidylinositol 3-kinase

" in MCE Product Catalog:

By Targets:	Apoptosis (1) Casein Kinase (1) DNA-PK (1) PI3K (6)
By Research Areas:	Cancer (5)

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Targets Recommended: PIKfyve PI4K

Cat. No.	Product Name	Target	Research Area	Chemical Structure

HY-109198

Zandelisib ME-401; PWT-143	PI3K	Cancer
Zandelisib (ME-401) 是一种 PI3K 抑制剂，选择性抑制 p110δ 的 IC₅₀ 值为 3.5 nM，详细信息请参考专利文献 WO2019183226 A1 中的化合物 1。Zandelisib 具有抗肿瘤作用。

HY-147419

Vulolisib	PI3K	Cancer
Vulolisib 是一种有效且具有口服活性的磷脂酰肌醇 3 激酶 (PI3K) 抑制剂，对 PI3Kα、PI3Kβ、PI3Kγ 和 PI3Kδ 的 IC₅₀ 分别为 0.2 nM、168 nM、90 nM 和 49 nM。对癌细胞具有抗增殖活性，也具有抗肿瘤活性。

HY-114457

Phosphatidylinositol 4,5-bisphosphate L-alpha-phosphatidylinositol-4,5-bisphosphate	PI3K	Others
Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate) 是细胞膜上的一种磷脂成分。Phosphatidylinositol 4,5-bisphosphate 作为一种主要信使，是磷脂酶 C (PLC) 和磷酸肌醇 3-激酶 (PI3K) 的底物。

HY-109029

Dezapelisib INCB040093	PI3K	Cancer
Dezapelisib (NCB040093) 是一种有效的磷脂酰肌醇 3-激酶 δ (PI3Kδ) 抑制剂。Dezapelisib 是一种很有前景的研究策略，可用于研究特定的 R/R B 细胞淋巴瘤。

HY-126083

17β-Hydroxywortmannin Wortmannin-17β-ol	PI3K	Others Cancer
17β-Hydroxywortmannin (Wortmannin-17β-ol) 是一种具有口服活性的 PI-3-kinase 激酶抑制剂，IC₅₀ 为 0.5 nM。17β-Hydroxywortmannin 可以抑制破骨细胞吸收，IC₅₀ 为 10 nM。17β-Hydroxywortmannin 具有抗肿瘤活性。

HY-10108A

LY294002 hydrochloride	PI3K Casein Kinase DNA-PK Apoptosis	Cancer
LY294002 hydrochloride 是一种有效的广谱 PI3K 抑制剂，对 P110α, P110δ 和 P110β 的 IC₅₀ 分别为 0.5, 0.57 和 0.97 μM。 IC50值分别为P110α、P110δ和P110β的0.5、0.57和0.97 μM。LY294002 hydrochloride 也能抑制 CK2 ，其 IC₅₀ 为 98 nM。LY294002 hydrochloride 可用于胰腺癌研究。

Phosphatidylinositol 4,5-bisphosphate L-alpha-phosphatidylinositol-4,5-bisphosphate	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	PI3K
Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate) 是细胞膜上的一种磷脂成分。Phosphatidylinositol 4,5-bisphosphate 作为一种主要信使，是磷脂酶 C (PLC) 和磷酸肌醇 3-激酶 (PI3K) 的底物。

Species:	Human (2)
Tag:	His (2) GST (2)
Source:	Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P701752

	PK3C3 Protein, Human (Sf9, His, GST) PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3; PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3; phosphatidylinositol 3-kinase p100 subunit; Phosphoinositide-3-kinase class 3; hVps34	Human	Sf9 insect cells
	PI3KC3 蛋白是 PI3K 复合物的催化亚基，介导磷脂酰肌醇 3-磷酸的形成。PI3KC3-C1 启动自噬体，而 PI3KC3-C2 促进自噬体成熟和内吞作用。PK3C3 Protein, Human (Sf9, His, GST) 是重组的 PK3C3 蛋白，由 Sf9 insect cells 表达，带有 N-8*His, N-GST 标签。PK3C3 Protein, Human (Sf9, His, GST) 全长 886 个氨基酸。

HY-P701744

	PIK3R3 Protein, Human (Sf9, His, GST) PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma; PI3-kinase regulatory subunit gamma; PI3K regulatory subunit gamma; PtdIns-3-kinase regulatory subunit gamma; phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; PI3-kinase subunit p55-gamma; PtdIns-3-kinase regulatory subunit p55-gamma; p55PIK	Human	Sf9 insect cells
	PIK3R3 蛋白通过其 SH2 结构域与磷酸化蛋白酪氨酸激酶相互作用，至关重要地调节其激酶活性。在胰岛素刺激期间，PIK3R3 与 IRS-1 结合。它作为具有 p110 催化亚基的异二聚体运行，与 AXL 相互作用，扩展其功能网络。PIK3R3 Protein, Human (Sf9, His, GST) 是重组的 PIK3R3 蛋白，由 Sf9 insect cells 表达，带有 N-8*His, N-GST 标签。PIK3R3 Protein, Human (Sf9, His, GST) 全长 460 个氨基酸。

产品对比


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Cat. No.	Product Name	Application	Reactivity

HY-P80868

PI3 Kinase p85 beta Antibody (YA688) p85; p85 beta; p85-BETA; P85B; P85B_HUMAN; phosphatidylinositol 3 kinase; phosphatidylinositol 3 kinase regulatory beta subunit; phosphatidylinositol 3 kinase regulatory subunit beta; phosphatidylinositol 3 kinase regulatory subunit polypeptide 2; Phospha	WB	Human, Mouse, Rat
PI3 Kinase p85 beta Antibody (YA688) is a non-conjugated and Mouse origined monoclonal antibody about 82 kDa, targeting to PI3 Kinase p85 beta (8D9). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P80867

PI3 Kinase p85 alpha Antibody (YA689) PIK3R1; GRB1; phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase s	WB, IHC-P	Human, Mouse, Rat
PI3 Kinase p85 alpha Antibody (YA689) is a non-conjugated and Mouse origined monoclonal antibody about 84 kDa, targeting to PI3 Kinase p85 alpha (1C8). It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P80846

Phospho-PI3 Kinase p85/p55 (Tyr467/Tyr199) Antibody 1 篇文献验证 PIK3R1; GRB1; phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase s	WB, IHC-F, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat, Monkey
Phospho-PI3 Kinase p85/p55 (Tyr467/Tyr199) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 84 kDa, targeting to Phospho-PI3 Kinase p85/p55 (Tyr467/Tyr199). It can be used for WB,IHC-F,IHC-P,ICC/IF,ELISA assays with tag free, in the background of Human, Mouse, Rat, Monkey.

HY-P83044

PIK3C3 Antibody (YA2789) phosphatidylinositol 3-kinase catalytic subunit type 3 (EC:2.7.1.137); PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3; phosphatidylinositol 3-kinase p100 subunit; Phosphoinositide-3-kinase class 3; hVps34; VPS34 antibodyPIK3C3；	WB, IHC-P	Human, Mouse, Rat

HY-P81211

phospho-PI3 Kinase p110 beta (Ser1070) Antibody PI3-kinase p110 subunit beta; p-PI3Kβ(Ser1070); PI 3-kinase C2β; p110 BETA; p110Beta; phosphatidylinositol 3 kinase catalytic beta polypeptide; phosphatidylinositol 4 5 bisphosphate 3 kinase 110 kDa catalytic subunit beta; phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit beta isoform; phosphatidylinositol-4; Phosphoinositide 3 kinase catalytic beta polypeptide; PI3 kinase p110 subunit beta; PI3-kinase subunit beta; PI3K; PI3K beta; PI3K-beta; PI3Kbeta; PI3KCB; PIK3C1; Pik3cb; PK3CB_HUMAN; PtdIns 3 kinase p110; PtdIns-3-kinase subunit beta; PtdIns-3-kinase subunit p110-beta; 5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; 5-bisphosphate 3-kinase catalytic subunit beta isoform.	WB; ELISA; IHC-P; IHC-F; IF	Human, Mouse, Rat(predicted: Chicken, Dog, Pig, Cow, Horse, Guinea Pig)
phospho-PI3 Kinase p110 beta (Ser1070) Antibody is an unconjugated, approximately 110-123 kDa, rabbit-derived, anti-phospho-PI3 Kinase p110 beta (Ser1070) polyclonal antibody. phospho-PI3 Kinase p110 beta (Ser1070) Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, rat, and predicted: chicken, dog, pig, cow, horse, guinea pig background without labeling.

HY-P81229

PI3 Kinase p110 beta Antibody PI3-kinase p110 subunit beta; p110 BETA; p110Beta; PI3K beta; phosphatidylinositol 3 kinase catalytic beta polypeptide; phosphatidylinositol 4 5 bisphosphate 3 kinase 110 kDa catalytic subunit beta; phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit beta isoform; phosphatidylinositol-4; Phosphoinositide 3 kinase catalytic beta polypeptide; PI3 kinase p110 subunit beta; PI3-kinase subunit beta; PI3K; PI3K beta; PI3K-beta; PI3Kbeta; PI3KCB; PIK3C1; Pik3cb; PK3CB_HUMAN; PtdIns 3 kinase p110; PtdIns-3-kinase subunit beta; PtdIns-3-kinase subunit p110-beta; 5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; 5-bisphosphate 3-kinase catalytic subunit beta isoform.	WB; ELISA; IHC-P; IHC-F; Flow-Cyt; ICC; IF	Human, Mouse, Rat(predicted: Dog, Cow, Horse, Rabbit)
PI3 Kinase p110 beta Antibody is an unconjugated, approximately 123 kDa, rabbit-derived, anti-PI3 Kinase p110 beta polyclonal antibody. PI3 Kinase p110 beta Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF expriments in human, mouse, rat, and predicted: dog, cow, horse, rabbit background without labeling.

HY-P81162

PIK3CA Antibody PI3 kinase p110 subunit alpha; caPI3K; MGC142161; MGC142163; p110 alpha; phosphatidylinositol 3 kinase catalytic alpha polypeptide; phosphatidylinositol 3 kinase catalytic 110 KD alpha; phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha isoform; Phosphoinositide 3 kinase catalytic alpha polypeptide; PI3 kinase p110 subunit alpha; PI3K; PI3KC A; PIK3C A; PK3CA; PtdIns 3 kinase p110; PI3-kinase P110α; PI3-kinase p110 subunit alpha; PI 3 kinase catalytic subunit alpha; PK3CA_HUMAN; PI3 kinase P110α.	WB; ELISA; IHC-P; IHC-F; ICC; IF	Human, Mouse, Rat(predicted: Chicken, Cow, Rabbit)
PIK3CA Antibody is an unconjugated, approximately 117 kDa, rabbit-derived, anti-PIK3CA polyclonal antibody. PIK3CA Antibody can be used for: WB, ELISA, IHC-P, IHC-F, ICC, IF expriments in human, mouse, rat, and predicted: chicken, cow, rabbit background without labeling.

HY-P81199

phospho-PI3KCA (Tyr317) Antibody PIK3CA(phospho Y317); PI3 kinase p110 subunit alpha; caPI3K; MGC142161; MGC142163; p110 alpha; phosphatidylinositol 3 kinase catalytic alpha polypeptide; phosphatidylinositol 3 kinase catalytic 110 KD alpha; phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha isoform; Phosphoinositide 3 kinase catalytic alpha polypeptide; PI3 kinase p110 subunit alpha; PI3K; PI3KC A; PIK3C A; PIK3CA; PK3CA; PtdIns 3 kinase p110; PI3-kinase P110α; PI3-kinase p110 subunit alpha; PI 3 kinase catalytic subunit alpha; PK3CA_HUMAN; PI3 kinase P110α.	WB; ELISA; IHC-P; IHC-F; IF	Human, Mouse(predicted: Rat)
phospho-PI3KCA (Tyr317) Antibody is an unconjugated, approximately 117 kDa, rabbit-derived, anti-phospho-PI3KCA (Tyr317) polyclonal antibody. phospho-PI3KCA (Tyr317) Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, and predicted: rat background without labeling.

HY-P81872

PI3 Kinase p110 delta Antibody (YA1617) PIK3CD; phosphatidylinositol 4; 5-bisphosphate 3-kinase catalytic subunit delta isoform; PI3-kinase subunit delta; PI3K-delta; PI3Kdelta; PtdIns-3-kinase subunit delta; phosphatidylinositol 4; 5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; PtdIns-3-kinase subunit p110-delta; p110delta	WB, ICC/IF	Human, Mouse, Rat

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